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http://dx.doi.org/10.1080/10428194.2018.1482546DOI Listing

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Patterns of use and safety of ibrutinib in real-life practice.

Br J Clin Pharmacol

March 2021

Pharmacologie Clinique et Vigilances, CHU de Poitiers, Poitiers, France.

Article Synopsis
  • The study aimed to gather real-life data on how ibrutinib is used and its safety profiles in patients between November 2014 and November 2018.
  • A total of 102 patients participated, mainly receiving ibrutinib for chronic lymphocytic leukemia (CLL), with 47.1% experiencing serious adverse drug reactions (SADRs) within the first year.
  • The findings highlighted that older patients (aged ≥80) and those with CLL had a higher risk of developing SADRs, indicating that they require closer monitoring during treatment.
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