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Presentation and Management of Silicone Lymphadenopathy: A Single Institutional Retrospective Cohort Study.
Aesthetic Plast Surg
January 2025
Division of Plastic and Reconstructive Surgery, DeWitt Daughtry Family Department of Surgery, Miami, FL, USA.
Introduction: Silicone Lymphadenopathy (SL) is a complication of breast implants that involves migration of silicone to nearby soft tissue/lymph nodes. Data on its clinical features and management is scarce. We aimed to identify the clinical presentation and management of SL.
View Article and Find Full Text PDFSilicone deposition and adverse pulmonary events secondary to breast implant rupture.
Radiol Case Rep
January 2025
Mater Dei Hospital, Triq id-Donaturi tad-Demm, l-Imsida, MSD2090, Malta, Europe.
Silicone breast implants are common but may be associated with a number of complications including implant rupture. This case reports a 38-year-old woman with bilateral breast implants who presented with breast unevenness, triggering a cascade of investigations that identified implant rupture. A computed tomography scan of the thorax showed subpleural enhancing nodules in the left lung of equal density as the implants, repeat computed tomography thorax months later showed no interval changes.
View Article and Find Full Text PDFDiagnostic value of the flare sign in predicting extracapsular extension in metastatic axillary lymph nodes and nodal status on breast magnetic resonance imaging.
Diagn Interv Radiol
November 2024
Tekirdağ Namık Kemal University Faculty of Medicine, Department of Surgical Oncology, Tekirdağ, Türkiye.
Article Synopsis
- * Analyzed MRI scans of 92 patients revealed that the "flare sign" in axillary fatty tissue is significantly related to ECE and other tumor characteristics, showing high specificity and positive predictive value.
- * The findings suggest that the flare sign is a valuable tool for preoperative evaluations, potentially aiding in surgical planning for breast cancer patients.
Are Clinically Node-Negative Patients with a Positive Preoperative Axillary Lymph Node Biopsy Appropriate Candidates for Sentinel Lymph Node Biopsy?
Ann Surg Oncol
January 2025
Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Article Synopsis
- The study investigates whether cN0 breast cancer patients with image-detected node metastases should undergo sentinel lymph node biopsy (SLNB) or directly have axillary lymph node dissection (ALND) or neoadjuvant chemotherapy (NAC).
- Of 90 patients analyzed, 73% had 1-2 positive sentinel lymph nodes (SLNs), while 27% had 3 or more, with certain factors like preoperative imaging abnormalities and extracapsular extension linking to the presence of more positive SLNs.
- The findings suggest that over 70% of these women do not need ALND and recommend using frozen section analysis to avoid unnecessary surgeries when multiple abnormal lymph nodes are found on scans.
Prediction of High Nodal Burden in Patients With Sentinel Node-Positive Luminal ERBB2-Negative Breast Cancer.
JAMA Surg
December 2024
Department of Surgery, Capio St Göran's Hospital, Stockholm, Sweden.
Importance: In patients with clinically node-negative (cN0) breast cancer and 1 or 2 sentinel lymph node (SLN) macrometastases, omitting completion axillary lymph node dissection (CALND) is standard. High nodal burden (≥4 axillary nodal metastases) is an indication for intensified treatment in luminal breast cancer; hence, abstaining from CALND may result in undertreatment.
Objective: To develop a prediction model for high nodal burden in luminal ERBB2-negative breast cancer (all histologic types and lobular breast cancer separately) without CALND.
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