AI Article Synopsis
- The study aimed to identify risk factors related to gestational diabetes mellitus (GDM) among women with singleton pregnancies at a hospital in Guangzhou, China, from 2012 to 2015.
- Of 8,381 women evaluated, 13.5% were diagnosed with GDM, with older age (35+) and obesity significantly increasing the risk, leading to the creation of a scoring system based on several factors such as age and body mass index.
- By using the risk scoring system, the number of women needing glucose tolerance testing could be reduced by over 25%, indicating a more efficient approach to GDM screening.
Article Abstract
Objective: To assess potential risk factors in identifying women at risk for gestational diabetes mellitus (GDM).
Methods: The present study included data collected as part of a prospective cohort study, and included women with singleton pregnancies who underwent initial prenatal examination at a tertiary women and children's hospital in Guangzhou, China between February 1, 2012, and December 31, 2015. Maternal characteristics and medical history were investigated to evaluate associations with GDM. A risk factor scoring system for the prediction of GDM was generated using logistic regression.
Results: Overall, 1129 (13.5%) of 8381 women were diagnosed with GDM. Women older than 35 years had a 3.95-fold increased risk of GDM (95% confidence interval 2.80-5.58) compared with women aged 16-25 years; obese women had a 6.54-fold higher risk (95% confidence interval 3.50-12.23) compared with underweight women. A risk scoring system was established based on age, body mass index, family history of diabetes, weight gain, and history of GDM. Screening for women with a score of 12 or more would have reduced the number undergoing oral glucose tolerance testing by 2131 (25.4%) patients with a sensitivity of 87% for GDM detection.
Conclusion: The assessment of risk factors for GDM could provide a foundation for improving risk-based screening strategies in this and similar populations.
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| http://dx.doi.org/10.1002/ijgo.12627 | DOI Listing |
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