AI Article Synopsis
- Midregional pro-atrial natriuretic peptide (MR-proANP) is a peptide discovered in 1981 that has significant functions in the cardiovascular system.
- The literature review examines its roles in bodily processes like natriuresis and diuresis, along with its implications for diagnosing and predicting cardiovascular diseases.
- Research indicates MR-proANP could also serve as a biomarker for other health issues beyond cardiovascular diseases, including diabetes and neurological disorders.
Article Abstract
Midregional pro-atrial natriuretic peptide (MR-proANP), first isolated in 1981, is a novel peptide with multiple biological functions, especially within the cardiovascular system. This peptide plays an important role in many processes, including natriuresis, diuresis, and other physiological and pathophysiological pathways in the human body. Several electronic databases (PubMed, EBSCO, Scopus, and ScienceDirect) were analyzed in the present literature review. The aim of this study was to elucidate the wide roles of MR-proANP, which can be analyzed because of the development of a new sandwich immunoassay, and to determine the possible diagnostic and prognostic implications of MR-proANP on cardiovascular disease and other disorders. The studies discussed in this literature review provide valuable data on the role of ANP in the pathogenesis, diagnostic process, prognosis, and potential therapeutic strategies for disease. Although ANP is mainly associated with cardiovascular disease, it may be used as a biomarker in diabetology, neurology, and metabolic disorders.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134641 | PMC |
| http://dx.doi.org/10.1177/0300060518786907 | DOI Listing |
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