AI Article Synopsis
- The study aimed to evaluate the effectiveness of trigger point manual therapy (TPMT) for chronic noncancer pain by analyzing relevant randomized controlled trials (RCTs).
- Researchers identified a total of 19 trials with 1,047 participants, focusing on various types of chronic pain, but found no significant short-term relief from pain.
- While there were improvements in function and patient-reported outcomes, the overall evidence supporting TPMT remains weak, leading to the conclusion that it cannot be recommended for chronic pain treatment at this time.
Article Abstract
Objective: To determine the effectiveness of trigger point manual therapy (TPMT) for reducing chronic noncancer pain and associated problems in adults, by analyzing all relevant randomized controlled trials (RCTs).
Data Sources: We searched databases and clinical trials registers from their inception to May 2017.
Study Selection: We included RCTs in any language that recruited patients older than 18, with pain of 3 months' duration or more. We assessed pain, function, and patient-reported improvement as outcomes.
Data Extraction: Two authors independently extracted and verified data. Meta-analysis was completed where possible, otherwise data were synthesized narratively.
Data Synthesis: We combined all data using a random-effects model and assessed the quality of evidence using GRADE. A total of 19 trials (involving 1047 participants) met inclusion criteria, representing TPMT treatment of musculoskeletal, pelvic, and facial pain. No effect was found for short-term pain relief (mean standardized difference -0.53; 95% confidence interval [CI], -1.08 to 0.02). One small study showed a longer-term benefit for pain (mean standardized difference -2.00; 95% CI, -3.40 to -0.60) but with low confidence in the effect. Significant gains emerged for function (mean standardized difference -0.77; 95% CI, -1.27 to -0.26) and in patient global response (odds ratio 3.79; 95% CI, 1.86-7.71) from 4 studies, but not for health-related quality of life.
Conclusions: Evidence for TPMT for chronic noncancer pain is weak and it cannot currently be recommended.
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| http://dx.doi.org/10.1016/j.apmr.2018.06.019 | DOI Listing |
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