AI Article Synopsis
- - The study aimed to assess how consistent optical coherence tomography angiography (OCTA) is when measuring the macular vessels in healthy eyes by using optical microangiography (OMAG) methods.
- - Forty healthy volunteers had their eyes scanned three times on two separate days, with multiple parameters evaluated to describe the superficial vascular network.
- - Results indicated that the OCTA measurements were highly repeatable and reproducible, shown by low coefficients of variation and high intraclass correlation coefficients across all parameters tested.
Article Abstract
Objective: The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography (OCTA) based on optical microangiography (OMAG) measurements of macular vessels in normal eyes.
Methods: In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA (Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network: vessel area density (VAD), vessel skeleton density (VSD), vessel diameter index (VDI), vessel perimeter index (VPI), vessel complexity index (VCI), flux, and foveal avascular zone (FAZ). Coefficient of variation (CV) and intraclass correlation coefficient (ICC) were calculated for evaluating intravisit and intervisit repeatability, as well as interobserver reproducibility.
Results: The measurements showed high repeatability [CVs ⪕ 4.2% (intravisit) and ⪕ 4.6% (intervisit)] and interobserver reproducibility (ICCs ⪖ 0.923) for all parameters.
Conclusion: This study demonstrated good repeatability and reproducibility of OCTA based on OMAG for the measurement of superficial vessel parameters in normal eyes.
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| http://dx.doi.org/10.3967/bes2018.054 | DOI Listing |
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