Hb Adana (HBA2: c.179G>A) is found worldwide but is extremely rare and carriers are asymptomatic, with red cell indices similar to α-thalassemia (α-thal) carriers. First line screening tests are unable to detect the unstable hemoglobin (Hb). Coinheritance with the α-thal (-α) deletion is herein presented and the challenges involving genetic counseling of couples carrying the mutations are discussed.
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| http://dx.doi.org/10.1080/03630269.2018.1466711 | DOI Listing |
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