Quality of life in Chinese patients with laryngeal cancer after radiotherapy.

Medicine (Baltimore)

Department of Otolaryngology, First Affiliated Hospital of Jiamusi University Department of otolaryngology, Second Affiliated Hospital of Jiamusi University, Jiamusi Department of Anatomy, Mudanjiang Medical University, Mudanjiang, China.

Published: July 2018

This retrospective study explored the quality of life (QoL) in Chinese patients with laryngeal cancer (LC) after radiotherapy.Fifty-nine eligible patients with Tis-T4 LC were included in this retrospective study. All patients received radiotherapy. Outcomes were measured by the core measure Questionnaire-C30 (QLQ-C30), and the disease-specific Head & Neck cancer module (QLQ-H&N35). All outcomes were assessed before and 3 months after the radiotherapy.Three months after the radiotherapy, all items of QLQ-C30 and QLQ-H&N35 scales changed significantly (P < .05), except the social functioning (P = .09), role activities (P = .81), and global (P = .12) in QLQ-C30 scale and social contacts (P = 1.00), teeth problems (P = .21), trismus (P = 1.00), and feeling ill (P = .07) in QLQ-H&N35 scale, compared with these items before the radiotherapy.The results of this study showed that most items of QoL changed significantly after 3 months of radiotherapy in Chinese patients with LC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086458PMC
http://dx.doi.org/10.1097/MD.0000000000011545DOI Listing

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