Iodine catalyzed C (sp)-H functionalization of tosylhydrazones with β-enamino esters under visible light irradiation for the synthesis of trisubstituted pyrroles has been described. The present method is also applicable to α- substituted tosylhydrazones to yield the tetra-substituted pyrroles.
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http://dx.doi.org/10.1021/acs.joc.8b00878 | DOI Listing |
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