A reduction of quinolines to synthetically versatile tetrahydroquinoline molecules with I and HBpin is described. In the presence of iodine (20 mol%) as a catalyst, reduction of quinolines and other N-heteroarenes proceeded readily with hydroboranes as the reducing reagents. The broad functional-group tolerance, good yields and mild reaction conditions imply high practical utility.
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| http://dx.doi.org/10.1039/c8cc04262d | DOI Listing |
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