Physiology-based ERPs in normal and abnormal states.

Biol Cybern

School of Physics, The University of Sydney, Sydney, NSW, 2006, Australia.

Published: October 2018

Evoked response potentials (ERPs) and other transients are modeled as impulse responses using physiology-based neural field theory (NFT) of the corticothalamic system of neural activity in the human brain that incorporates synaptic and dendritic dynamics, firing response, axonal propagation, and corticocortical and corticothalamic pathways. The properties of model-predicted ERPs are explored throughout the stability zone of the corticothalamic system, and predicted time series and wavelet spectra are also analyzed. This provides a unified treatment of predicted ERPs for both normal and abnormal states within the brain's stability zone, including likely parameters to represent abnormal states of reduced arousal.

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http://dx.doi.org/10.1007/s00422-018-0766-xDOI Listing

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