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Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium. | LitMetric

Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium.

Nutrients

Department of Pharmacology and Therapeutics and Department of Physiology, University College Cork, T12 K8AF Cork, Ireland.

Published: July 2018

AI Article Synopsis

Article Abstract

Magnesium is an essential mineral involved in a range of key biochemical pathways. Several magnesium supplements are present on the market and their degree of bioavailability differs depending on the form of magnesium salt used. Aquamin-Mg is a natural source of magnesium, containing 72 additional trace minerals derived from the clean waters off the Irish coast. However, the in vitro bioaccessibility and bioavailability of Aquamin-Mg in comparison with other supplement sources of magnesium has yet to be tested. Aquamin-Mg, magnesium chloride (MgCl₂) and magnesium oxide (MgO) were subjected to gastrointestinal digestion according to the harmonized INFOGEST in vitro digestion method and in vitro bioavailability tested using the Caco-2 cell model. Magnesium concentration was measured by atomic absorption spectrophotometry (AAS). Magnesium recovery from both Aquamin-Mg and MgCl₂ was greater than for MgO. Magnesium from all three sources was transported across the epithelial monolayer with Aquamin-Mg displaying a comparable profile to the more bioavailable MgCl₂. Our data support that magnesium derived from a marine-derived multimineral product is bioavailable to a significantly greater degree than MgO and displays a similar profile to the more bioavailable MgCl₂ and may offer additional health benefits given its multimineral profile.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073474PMC
http://dx.doi.org/10.3390/nu10070912DOI Listing

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