Objectives: To investigate intra- and inter-observer repeatability of aortic annulus CT measurements for transcatheter aortic valve replacement (TAVR) by readers with different levels of experience and evaluate the impact of different multi-reader paradigms to improve prosthesis sizing.
Methods: 82 TAVR screening CTAs were evaluated twice by three raters with six (R1 = radiologist), three (R2 = 3D-laboratory technician) or zero (R3 = medical student) years of experience. Results were translated into hypothetical TAVR size recommendations. Intra- and inter-observer repeatability between single readers and three different multi-reader paradigms ([A]: two readers, [B]: three readers, or [C]: two readers + an optional third reader) were evaluated.
Results: Intra-observer variability did not differ significantly (range: 50.1-67.8mm2). However, we found significant differences in mean inter-observer variance (p = 0.001). Multi-reader paradigms led to significantly increased precision (lower variability) for scenarios [B] and [C] (p = 0.03, p < 0.05). Compared to single readers, all multi-reader strategies clearly lowered the rate of discrepant device size categorization between repeated measurements (22-26% to 5-10%).
Conclusions: Aortic annulus CT measurements for TAVR are highly reproducible. Multi-reader strategies provide higher precision than evaluations from single readers with different levels of experience and could effectively be implemented with two readers and an optional third reader (Paradigm C) in a clinical setting.
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http://dx.doi.org/10.1016/j.ejrad.2018.06.003 | DOI Listing |
Acad Radiol
November 2024
Qure.ai Technologies Pvt. Ltd., Floor 6, Wing E, Times Square, Mumbai, Maharashtra, India, 400059 (B.K.).
PLoS One
October 2020
Department of Computer Science, The University of Manchester, Manchester, United Kingdom.
Drug-induced long QT syndrome (diLQTS), characterized by a prolongation of the QT-interval on the electrocardiogram (ECG), is a serious adverse drug reaction that can cause the life-threatening arrhythmia Torsade de Points (TdP). Self-monitoring for diLQTS could therefore save lives, but detecting it on the ECG is difficult, particularly at high and low heart rates. In this paper, we evaluate whether using a pseudo-colouring visualisation technique and changing the coordinate system (Cartesian vs.
View Article and Find Full Text PDFAcad Radiol
March 2020
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Rationale And Objectives: The purpose of this study was to validate a Bayesian statistical model of item response theory (IRT). IRT was used to evaluate a new modality (temporal subtraction, TS) in observer studies of radiologists, compared with a conventional modality (computed tomography).
Materials And Methods: From previously published papers, we obtained two datasets of clinical observer studies of radiologists.
Eur J Radiol
August 2018
Department of Radiology, UW - School of Medicine and Public Health, Madison, WI, USA; Department of Medical Physics, UW - School of Medicine and Public Health, Madison, WI, USA; Department of Pediatrics, UW - School of Medicine and Public Health, Madison, WI, USA.
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