Kingella kingae typically causes musculoskeletal infection in young children between the ages of 6 months and 4 years who may be in close contact with other similarly aged children who are colonized with the organism in their oropharynx. Kingella infections have rarely been described in older individuals with chronic medical conditions or immune compromise. This is a case report of a healthy, older child who developed an invasive infection due to Kingella kingae. Clinical and laboratory details are provided of an otherwise healthy 11-year-old female who developed an acute onset of septic arthritis of her shoulder. The organism was identified by culture and 16S polymerase chain reaction. Her clinical course necessitated an antibiotic change after the organism was correctly identified. The affected child had close contact with a 2-year-old sibling who recently had a viral upper respiratory infection. This case illustrates the potential for Kingella kingae to rarely cause invasive infection in older, healthy children. Supplemental laboratory techniques may be helpful to identify this organism. Although it is reasonable to limit the antibiotic spectrum for older children, clinicians should be aware of this possibility, particularly if there is a history of close contact with young children.

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http://dx.doi.org/10.1093/jpids/piy063DOI Listing

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Article Synopsis
  • Correct diagnosis and treatment of septic arthritis (SA) are crucial to avoid long-term health issues, and recent research is focusing on new biomarkers to address diagnostic challenges.
  • The rising incidence of septic arthritis caused by Kingella Kingae complicates diagnosis, as it presents with atypical signs compared to traditional infections, and magnetic resonance imaging is becoming an important tool for accurate assessment.
  • While there are studies on less invasive treatments and investigations into SA in various joints (beyond just the hip and knee), caution is advised regarding treatment outcomes, especially in young children where diagnosis can be particularly challenging.
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Purpose Of Review: For pediatric osteomyelitis and septic arthritis, 10-24% of cases occur in the upper extremity (UE). Due to delays in presentation and diagnosis, UE infections are often more complex and severe than infections of the lower extremity (LE). This review evaluates the literature from the past 6 years related to pediatric osteomyelitis and septic arthritis of the UE and provides a guide for professionals managing these conditions in children.

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