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A unique chemically induced proximity method is engineered based on mutant antibody VL domain using a fluorogenic malachite green derivative as the inducer, which gives fluorescent signals upon VL domain dimerization while simultaneously inducing downstream biological effects.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233874 | PMC |
| http://dx.doi.org/10.1021/acs.bioconjchem.8b00415 | DOI Listing |
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