Recently, short-term traffic prediction under conditions with corrupted or missing data has become a popular topic. Since a road section has predictive power regarding the adjacent roads at a specific location, this paper proposes a novel hybrid convolutional long short-term memory neural network model based on critical road sections (CRS-ConvLSTM NN) to predict the traffic evolution of global networks. The critical road sections that have the most powerful impact on the subnetwork are identified by a spatiotemporal correlation algorithm. Subsequently, the traffic speed of the critical road sections is used as the input to the ConvLSTM to predict the future traffic states of the entire network. The experimental results from a Beijing traffic network indicate that the CRS-ConvLSTM outperforms prevailing deep learning (DL) approaches for cases that consider critical road sections and the results validate the capability and generalizability of the model when predicting with different numbers of critical road sections.
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http://dx.doi.org/10.3390/s18072287 | DOI Listing |
Cytotechnology
April 2025
Department of Critical Care Medicine, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), No. 1017, North Dongmen Road, Luohu District, Shenzhen, 518020 Guangdong China.
This study aimed to investigate the role of circular RNAs (circRNAs) in sepsis-induced acute gastrointestinal injury (AGI), focusing on their potential as biomarkers and their involvement in disease progression. Peripheral blood samples from 14 patients with sepsis-induced AGI and healthy volunteers were collected. RNA sequencing was performed to profile circRNA and miRNA expression.
View Article and Find Full Text PDFPak J Med Sci
January 2025
Inzimam Ul Haq Postgraduate trainee, Department of ENT, MTI Khyber Teaching Hospital, University Road Peshawar, Pakistan.
Background & Objective: Chronic suppurative otitis media is a fatal condition owing to its propensity for intracranial extension. The inadvertent use of antibiotics has led to resistance among causative organisms. The objectives of this study were to determine causative bacteria, their antibiotic resistance and susceptibility patterns, and their response to antibiotics after a one-month follow-up.
View Article and Find Full Text PDFMater Today Bio
February 2025
China Uruguay Bio-Nano Pharmaceutical Joint Laboratory, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, 308 Ningxia Road, Qingdao, 266071, Shandong, China.
Well-designed artificial scaffolds are urgently needed due to the limited self-repair capacity of bone, which hampers effective regeneration in critical defects. Optimal scaffolds must provide physical guidance to recruit cells and immune regulation to improve the regenerative microenvironment. This study presents a novel scaffold composed of dual-sided centripetal microgrooved poly(D,L-lactide-co-caprolactone) (PLCL) film combined with a dynamic hydrogel containing prednisolone (PLS)-loaded Prussian blue nanoparticles (PB@PLS).
View Article and Find Full Text PDFACS Omega
January 2025
School of Bio-Chemical Engineering and Technology, Sirindhorn International Institute of Technology, Thammasat University, 99 Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani 12120, Thailand.
The integration of molecular docking and AM1 calculations has elucidated the complexation behavior of butylone enantiomers with methylated β-cyclodextrin derivatives. Our study reveals that butylone can adopt two distinct conformations within the β-cyclodextrin cavity, with one conformation being preferentially stabilized due to its favorable binding energy. This conformation preference is influenced by the methylation at the O2, O3, and O6 positions of β-cyclodextrin, which significantly affects complex stability and solvation properties.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Oncology, The First Affiliated Hospital of Zhengzhou University, No.1 Eastern Jianshe Road, Zhengzhou, 450052, Henan, China.
Background: Cuproptosis is a unique form of cell death that is dependent on copper, which is fundamentally different from other recognized forms of cell death. However, the molecular and immune characteristics in cuproptosis-defined subgroups of cholangiocarcinoma (CCA) remain to be further illustrated.
Methods: We conducted a comprehensive investigation into the genetic and transcriptional variation, prognostic significance, and expression profiles of 16 cuproptosis-related genes (CRGs).
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