AI Article Synopsis
- Spindle cell xanthogranuloma is a rare form of juvenile xanthogranuloma, primarily found in adults, and typically appears as papulonodules.
- A case is described involving a 10-year-old boy with a dark red, dome-shaped papule on his nose that resembled a vascular lesion.
- Histological analysis showed spindle-shaped histiocytes and positive staining for CD68 and Ki-67, with no actual vascular features present, marking the first known instance of this condition mimicking an angiomatous lesion.
Article Abstract
Spindle cell xanthogranuloma is a rare variant of juvenile xanthogranuloma that most commonly presents in adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. Histopathology revealed spindle-shaped histiocytes in a storiform pattern that stained positive for cluster of differentiation 68 (CD68) and the nuclear antigen Ki-67. No vascular features were found. To our knowledge, this is the first reported spindle cell xanthogranuloma to mimic an angiomatous lesion.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037337 | PMC |
| http://dx.doi.org/10.7759/cureus.2595 | DOI Listing |
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