Dilemmas associated with local allergic rhinitis.

Postepy Dermatol Alergol

Unit of Environmental Hazard Prevention and Allergology, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland.

Published: June 2018

AI Article Synopsis

  • Local allergic rhinitis (LAR) occurs in patients without systemic markers of allergy, raising questions about its underlying mechanisms.
  • Current theories range from considering LAR an allergic reaction to viewing it as a spontaneous process in the nasal mucosa.
  • Future research aims to clarify the inflammatory reactions involved in LAR, potentially leading to improved diagnostic methods for rhinitis.

Article Abstract

Local allergic rhinitis (LAR) in patients with no systemic markers of atopy is a very interesting phenomenon due to the lack of any definitive explanation for the mechanism of this IgE-dependent reaction. Some of the recent attempts to explain this phenomenon consider LAR to be closely associated with an allergic reaction, some suggest that this phenomenon is a spontaneous process in the nasal mucosa. Future attempts to elucidate the complexity of inflammatory reactions will undoubtedly establish a clear differential diagnostics algorithm for rhinitis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041707PMC
http://dx.doi.org/10.5114/ada.2018.76215DOI Listing

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