Microcystins (MCs) pollution has quickly risen in infamy and has become a major problem to public health worldwide. MCs are a group of monocyclic hepatotoxic peptides, which are produced by some bloom-forming cyanobacteria in water. More than 100 different MCs variants posing a great threat to animals and humans due to their potential carcinogenicity have been reported. To reduce MCs risks, the World Health Organization has set a provisional guideline of 1 μg/L MCs in human's drinking water. This paper provides an overview of exposure routes of MCs into the human system and health effects on different organs after MCs exposure including the liver, intestine, brain, kidney, lung, heart and reproductive system. In addition, some evidences on human poisoning and deaths associated with MCs exposure are presented. Finally, in order to protect human life against the health threats posed by MCs, this paper also suggests some directions for future research that can advance MCs control and minimize human exposure to MCs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.toxicon.2018.07.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Manifestations.
Alzheimers Dement
December 2024
Universidad Simón Bolívar, Barranquilla, Colombia.
Background: Quantitative Electroencephalography (qEEG) plays a pivotal role in the assessment and categorization of cognitive impairment (CI). The integration of qEEG markers with neuropsychological test scores can predict rapid cognitive decline in neurodegenerative diseases. The aim of this study was to correlate qEEG findings with the neuropsychological profile in patients with CI from the Colombian Caribbean.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Universidad Simón Bolívar, Barranquilla, Colombia.
Background: The neuropsychological profile within indigenous communities is a complex interplay of cultural, social, and environmental factors that significantly influence cognitive functioning and distinct neuropsychological patterns. The aim of this study was to assess the neuropsychological profile in the Wayuu indigenous population.
Methods: A cross-sectional study.
Clinical Manifestations.
Alzheimers Dement
December 2024
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Background: Subjective cognitive decline (SCD) is defined by the presence of cognitive complaints in cognitively unimpaired (CU) individuals. Despite being part of the continuum of a neurodegenerative disease, the cause of the cognitive complaint is quite heterogeneous. Sleep disturbances may be associated with cognitive complaints and even objective cognitive decline.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil.
Background: Mild Behavioral Impairment (MBI) is a construct developed to capture neuropsychiatric symptoms in individuals in early stages of neurodegenerative diseases. The assessment of MBI in individuals with preclinical cognitive manifestations in Brazil is still quite limited. The aim of this study is to evaluate the MBI-Checklist (MBI-C) in individuals with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) in the Brazilian Subjective Cognitive Decline (BRASCODE) cohort in southern Brazil.
View Article and Find Full Text PDFThe Cumulative Burden of Social Risk Factors and 10-Year Change in Quality of Life.
J Gerontol A Biol Sci Med Sci
December 2024
Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Background: Social risk factors are linked to adverse health outcomes, but their total impact on long-term quality of life is obscure. We hypothesized that a higher burden of social risk factors is associated with greater decline in quality of life over 10 years.
Methods: We examined associations between social risk factors count and decline >5 points in (i) physical component summary, and (ii) mental component summary scores from the Short Form-12 among Black and White participants in the Reasons for Geographic and Racial Differences in Stroke study (n = 14 401).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!