AI Article Synopsis

  • Progressive disseminated histoplasmosis (PDH) is a severe AIDS-related illness that can be fatal without quick treatment, complicating its diagnosis due to varied symptoms in non-endemic areas.
  • A case is discussed involving a newly diagnosed HIV patient who developed PDH with haemophagocytic syndrome, illustrating the seriousness of the condition.
  • The text includes a thorough review of PDH in HIV patients, covering aspects like its prevalence, symptoms, diagnostic mechanisms, and treatment strategies.

Article Abstract

Progressive disseminated histoplasmosis (PDH) is an AIDS-defining illness with a high lethality rate if not promptly treated. The wide range of its possible clinical manifestations represents the main barrier to diagnosis in non-endemic countries. Here we present a case of PDH with haemophagocytic syndrome in a newly diagnosed HIV patient and a comprehensive review of disseminated histoplasmosis focused on epidemiology, clinical features, diagnostic tools and treatment options in HIV-infected patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039081PMC
http://dx.doi.org/10.4084/MJHID.2018.040DOI Listing

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