Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.surg.2018.05.054 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Perioperative Antibiotic Choice Does Not Affect Wound Complications in the Operative Treatment of Ankle Fractures.
Cureus
November 2024
Pediatrics, Good Samaritan University Hospital, West Islip, USA.
Background and aims Ankle injuries are one of the most common lower extremity traumas reported, with nearly half needing surgical intervention. For those who undergo surgical treatment, surgical site infection (SSI) is not a rare complication. Cefazolin is the recommended preoperative surgical chemoprophylaxis for surgical site infection.
View Article and Find Full Text PDFSafety, tolerability and pharmacokinetics of subcutaneous cefazolin as an alternative to intravenous administration.
J Antimicrob Chemother
December 2024
Department of Infectious Diseases, Fiona Stanley Fremantle Hospitals Group, Murdoch, Western Australia 6150, Australia.
Background: Subcutaneous (SC) administration of antibiotics is a practical alternative to IV administration. Cefazolin is widely used for skin and soft tissue infections and other complex infections by IV administration.
Methods: In this prospective, cross-over self-controlled study, a single dose of SC cefazolin was administered to 15 stable inpatients established on IV cefazolin as part of their management plan.
Cefazolin shifts the kidney microbiota to promote a lithogenic environment.
Nat Commun
December 2024
Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, OH, USA.
Clinical studies of the urinary tract microbiome, termed urobiome, suggest a direct, antibiotic-dependent, impact of the urobiome on kidney physiology. However, evidence for kidney bacteria comes from indirect sources or infected tissue. Further, it is unclear how antibiotics impact kidney bacteria.
View Article and Find Full Text PDFEvaluation of cephalosporin allergy: Survey of drug allergy experts.
J Allergy Clin Immunol Glob
February 2025
Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Background: Since the publication of the 2022 Drug Allergy Practice Parameters (DAPP) of the American Academy of Allergy, Asthma & Immunology (AAAAI) and American College of Allergy, Asthma & Immunology (ACAAI), it is unclear the extent to which the simplified and risk-stratified evaluation of cephalosporin allergy has been incorporated into allergy practice.
Objective: We aimed to assess current cephalosporin allergy testing practices using real case examples.
Methods: An 18-question REDCap survey was sent to the 136 members of the Adverse Reactions to Drugs, Biologics and Latex (ARDBL) Committee of the AAAAI between February and April 2023.
Exploring the Landscape of Perioperative Immediate Hypersensitivity: A Comprehensive 6-Year Monocentric Observational Analysis on Epidemiology and Risk Factors.
Int Arch Allergy Immunol
November 2024
Anaesthesiology and Critical Care Medicine Department, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.
Introduction: Perioperative immediate hypersensitivity (POH) is a rare complication estimated at 1/10,000 anaesthesia. The objective of our study was to investigate the risk factors of POH over a 6-year period in a French teaching hospital.
Materials And Methods: A single-centre retrospective descriptive epidemiological study of patients treated in the operating room from January 2016 to December 2021 with and without POH.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!