Navigation to a previously visited reward site requires a reliable and accurate spatial memory. In this issue of Neuron, Gauthier and Tank (2018) use two-photon calcium imaging to uncover a discrete hippocampal subpopulation specialized for encoding reward location.
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| http://dx.doi.org/10.1016/j.neuron.2018.06.037 | DOI Listing |
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Network analysis combined with genome-wide association study helps identification of genes related to amino acid contents in soybean.
BMC Genomics
January 2025
Department of Horticulture and Crop Science, The Ohio State University, Columbus, OH, 43210, USA.
Background: Additional to total protein content, the amino acid (AA) profile is important to the nutritional value of soybean seed. The AA profile in soybean seed is a complex quantitative trait controlled by multiple interconnected genes and pathways controlling the accumulation of each AA. With a total of 621 soybean germplasm, we used three genome-wide association study (GWAS)-based approaches to investigate the genomic regions controlling the AA content and profile in soybean.
View Article and Find Full Text PDFElucidation of the fine structure and anti-breast tumor activity of a glucomannan from the pseudobulbs of Pleione bulbocodioides.
Carbohydr Polym
March 2025
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address:
Pseudobulbs of Pleione bulbocodioides have been used as traditional Chinese medicine for a long time to treat cancers through decoction with water. However, as its main water-soluble ingredient, the structure of polysaccharide has not been elucidated yet. To obtain its polysaccharide with antitumor activity, a series of isolation, structural identification and antitumor evaluation experiments were performed.
View Article and Find Full Text PDFIdentification and discrimination of human keratinized tissues using ATR-FTIR and chemometrics.
Forensic Sci Int
January 2025
Forensic Science Department, Kristu Jayanti College (autonomous), Bangalore, India. Electronic address:
In forensic investigations, human keratinized tissues like skin and nails are commonly encountered as trace evidence, yet the use of vibrational spectroscopy for their identification and differentiation has been underexplored. This research utilized ATR-FTIR to distinguish between human nails and skin samples collected from a group of 50 participants, employing advanced chemometric analysis techniques. The spectral signatures of human keratinized tissues, such as nails and skin, exhibit similarities consistent with previous studies.
View Article and Find Full Text PDFDifferences in tumor size, clinical, demographic, and socioeconomic profiles of central nervous system tumors among a racially diverse cohort: A retrospective case-control study.
Surg Neurol Int
December 2024
Department of Medicine, University of Hawai'i at Mānoa, John A. Burns School of Medicine, Honolulu, Hawaii, USA.
Background: One avenue to improve outcomes among brain tumor patients involves the mitigation of healthcare disparities. Investigating clinical differences among brain tumors across socioeconomic and demographic strata, such can aid in healthcare disparity identification and, by extension, outcome improvement.
Methods: Utilizing a racially diverse population from Hawaii, 323 cases of brain tumors (meningiomas, gliomas, schwannomas, pituitary adenomas, and metastases) were matched by age, sex, and race to 651 controls to investigate the associations between tumor type and various demographic, socioeconomic, and medical comorbidities.
"Older adults with acute coronary syndrome: The impact of frailty and nutritional status on in-hospital complications".
Eur J Cardiovasc Nurs
January 2025
Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), 29010 Málaga, Spain.
Aims: The optimal management of older patients with acute coronary syndrome (ACS) remains unclear. The most effective evaluation methods for frailty and malnutrition are yet to be delineated, despite being proposed as predictors of adverse outcomes. Consequently, this study aims to assess the significance of these factors in predicting in-hospital complications within this population.
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