AI Article Synopsis
- Sagliker syndrome is a rare condition linked to renal osteodystrophy caused by untreated secondary hyperparathyroidism, presenting severe skeletal and facial deformities in affected individuals.
- A case study of a 44-year-old male patient demonstrated high levels of parathyroid hormone (PTH) and alkaline phosphatase (ALP), leading to the identification of this rare syndrome.
- The findings emphasize the need for early diagnosis and treatment in young patients with chronic renal issues, as timely intervention can prevent serious complications like bone abnormalities and cardiovascular problems.
Article Abstract
Sagliker syndrome is a rare form of renal osteodystrophy resulted from untreated secondary hyperparathyroidism. It is described by severe skeletal deformities, high level of PTH in patients with chronic renal failure, and deformed face. This paper reports a 44-year-old male patient with the mentioned characteristics. In addition to the unique clinical features, high levels of ALP and PTH hormones encouraged us to search for syndrome-like a disease, which clinically and paraclinically matched the Sagliker syndrome. This case highlights the importance of clinicians' attention for early monitoring and appropriate treatment as it is shown to be effective in preventing irreversible complications such as soft tissue and bone abnormalities and cardiovascular impairment in patients with Sagliker syndrome. Therefore, considering the syndrome is recommended as one of the diagnostic hypothesis in young patients with renal insufficiency, secondary hyperparathyroidism, and skeletal deformities.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038973 | PMC |
| http://dx.doi.org/10.22038/aojnmb.2018.10567 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!