AI Article Synopsis
- Diastolic dysfunction can signal early myocardial ischemia, often before ECG changes occur.
- The study investigated the relationship between ST segment shifts and diastolic dysfunction in patients with acute myocardial infarction.
- While most diastolic indices showed no significant correlation with ST segment shifts, certain parameters like the E/A ratio and deceleration time had some direct correlation, indicating a complex relationship between ECG changes and heart function in acute coronary syndrome.
Article Abstract
Background: Diastolic dysfunction is the early sign of myocardial ischemia that usually occurs earlier than ECG changes.
Aim Of The Study: To determine the existence of a correlation between ST segment shift and diastolic dysfunction among patients with AMI.
Methods: Fourty six patients with significant ST segment elevation or depression and having symptoms of acute myocardial infarction for <12 h were enrolled in this study. Patients were examined for serial ECG, cardiac enzymes, and echocardiography.
Results: There was no significant correlation between ST segment elevation or depression and majority of the diastolic indices. Few diastolic parameters; such as, E/A ratio of the mitral valve and deceleration time of the tricuspid valve showed a direct correlation with the ECG changes. Whereas, the Tei Index of the LV function showed a borderline correlation to the ST segment elevation at discharge.
Conclusion: Overall, there was no correlation between either ST segment elevation or depression and the LV or RV diastolic function in patients with acute coronary syndrome (ACS). Improvement of the ST segment total score was associated with improvement of the diastolic function grades at discharge. Moreover, this association has shown an evidence of dose response relationship, the more improvement in total score at discharge the more improvement in diastolic function grade level.
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| http://dx.doi.org/10.1016/j.jelectrocard.2018.03.006 | DOI Listing |
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