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Severe Lymphopenia Predicts Poorer Survival in Patients With Rectal Cancer Undergoing Neoadjuvant Chemoradiation.
Cancer J
January 2025
From the Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA.
Purpose: Chemoradiation-induced lymphopenia is common and associated with poorer survival in multiple solid malignancies. However, the association between chemoradiation-related lymphopenia and survival outcomes in rectal cancer is yet unclear. The objective of this study was to evaluate the prognostic impact of lymphopenia and its predictors in patients with rectal cancer undergoing neoadjuvant chemoradiation.
View Article and Find Full Text PDFThe publication fate of abstracts awarded prizes at European Society of Paediatric Radiology annual scientific meetings.
Pediatr Radiol
January 2025
School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Background: The European Society of Paediatric Radiology (ESPR) awards prizes for outstanding work presented at their annual scientific meetings. The proportion of ESPR prize-winning abstracts to journal publications is not known. Contextualising abstract-to-publication proportions by evaluating publication experience can yield valuable insights and actionable outcomes to support researchers in overcoming barriers to journal publication.
View Article and Find Full Text PDF[Pharmacotherapeutic treatment in an adolescent with bipolar disorders].
Tijdschr Psychiatr
January 2025
Bipolar disorder (BD) frequently occurs in children and adolescents, but pharmacological treatment in this group presents significant challenges. Clinicians often struggle to find appropriate treatment guidelines due to the primary focus of current guidelines on adults, leaving specific recommendations for the acute and maintenance treatment of BD in children and adolescents either insufficient or entirely absent. This gap is partly due to the lack of targeted studies in this age group, leading practitioners to rely on clinical experience and studies conducted in adults.
View Article and Find Full Text PDFOutcomes for Gastrectomy During Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Non-Gastric Primaries: A 30-Year Experience.
J Am Coll Surg
January 2025
Section of Surgical Oncology, Department of General Surgery.
Introduction: Cytoreductive surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) can improve survival for patients with peritoneal surface malignancy. Completeness of cytoreduction correlates with prognosis. The role of gastrectomy in these patients is not well described.
View Article and Find Full Text PDFDigital phenotyping of social functioning and employment in people with schizophrenia: Pilot data from an international sample.
Psychiatry Clin Neurosci
January 2025
Division of Digital Psychiatry, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Aim: Individuals living with schizophrenia experience significant impairments in social functioning. As a major clinical outcome, social functioning requires appropriate measurement tools that can capture its dynamic nature. Digital phenotyping, using smartphone technology to collect high volume ecologically valid data, can potentially capture these facets.
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