AI Article Synopsis

  • High-intensity focused ultrasound (HIFU) coupled with MRI guidance offers a noninvasive method for precisely targeting and ablation solid tumors.
  • A specially designed MRI-compatible 1-MHz transducer minimizes skin burn risk during treatment and achieves volumetric ablation efficiently.
  • Experiments showed effective necrosis in ex vivo pork tissue with no damage to surrounding fat, and the MRI technique accurately quantified the treatment region without interference from HIFU.

Article Abstract

High-intensity focused ultrasound (HIFU) under magnetic resonance imaging (MRI) guidance can achieve a noninvasive and precise ablation of the solid tumor. In the study, an MRI-compatible 1-MHz 16-channel ring-shaped transducer was developed to minimize the burn risk of breast skin and perform volumetric ablation for short treatment time. The measured electroacoustic conversion efficiency of the transducer was 50.90% ± 5. The transducer could produce a point and a quasi-hollow-cylinder lesion in a thermal-sensitive phantom or an ex vivo pork by tuning the phase of each element. It may achieve volumetric ablation of 1.5 cm when the point lesion is located inside the hollow lesion. Ex vivo ablation experiments showed that the transducer could cause a coagulative necrosis in the pork from the surrounded subcutaneous fat by 5 mm without fat damage. The temperature and region of the pork ablation were quantified by MRI technique. There was no MRI interference from HIFU and vice versa while both systems operated concurrently.

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Source
http://dx.doi.org/10.1109/TUFFC.2018.2841418DOI Listing

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