Objectives: This paper examines how people express personal mood concurrently with those connected with them by one or two degrees of separation.
Design: Participatory cohort study.
Setting: Online contact diary.
Participants: 133 participants kept online diaries for 7 months in 2014, which included 127 455 contacts with 12 070 persons.
Main Outcome Measures: Diary keepers rated a contacted person's mood during each specific contact, as well as the strength of ties between any pairs of such contacted persons. Such rich information about ties and contacts enable us to construct a complete contact network for each diary keeper, along with the network members' mood and tie strength. We calculate one's overall mood by that person's average mood score during the study period and take the shortest path between any given pair of contacted persons as the degree of separation. We further assume that two connecting persons in a contact network have made contact with each other during the study period, which allows us to examine whether and how personal moods occur concurrently within these contact networks.
Results: Using mixed-effects models while controlling for covariates at individual, tie and contact levels, we show that personal mood score positively and significantly correlates with the average mood among those directly tied to the person. The same effect remains positive and significant for those connected to the person by two degrees, although the effect size is reduced by about one-half. The mood of anyone separated by more than two degrees is statistically irrelevant.
Conclusions: Applying network perspectives and rich data at both tie and contact levels to inquiries about subjective well-being, the current study sheds new light on how an improved diary approach can help explain the sophisticated ways in which individuals express their personal moods concurrently during social interactions in everyday life, contact by contact.
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http://dx.doi.org/10.1136/bmjopen-2017-020600 | DOI Listing |
Genome Biol Evol
January 2025
Department of Agricultural Biology, 1177 Campus Delivery, Colorado State University, Fort Collins, CO, 80523, USA.
This report presents two phased chromosome-scale genome assemblies of allotetraploid Salsola tragus (2n=4x=36) and fills the current genomics resource gap for this species. Flow cytometry estimated 1C genome size was 1.319 Gbp.
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January 2025
Mental Health Center Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.
Purpose: People living in supported accommodation often have complex care needs, including longer-term mental health illness and physical health comorbidities. Effective coordination between health and supported accommodation services is crucial to address these needs. However, evidence on the effectiveness of healthcare interventions in this setting remains limited.
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January 2025
Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada; Department of Human Genetics, McGill University, Montréal, Québec, Canada; 5 Prime Sciences Inc, Montréal, Quebec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, QC, Canada; Department of Medicine, McGill University, Montréal, Québec, Canada; Department of Twin Research, King's College London, London, UK. Electronic address:
Identifying novel, high-yield drug targets is challenging and often results in a high failure rate. However, recent data indicates that leveraging human genetic evidence to identify and validate these targets significantly increases the likelihood of success in drug development. Two recent papers from Open Targets claimed that around half of FDA-approved drugs had targets with direct human genetic evidence.
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January 2025
Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM 87131, USA.
Interactions between bacteriophages with mammalian immune cells are of great interest and most phages possess at least one molecular pattern (nucleic acid, sugar residue, or protein structure) that is recognizable to the immune system through pathogen associated molecular pattern (PAMP) receptors (i.e., TLRs).
View Article and Find Full Text PDFViruses
January 2025
Global Health Program, Washington State University Global Health-Kenya, Nairobi 00200, Kenya.
Human outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) are more common in Middle Eastern and Asian human populations, associated with clades A and B. In Africa, where clade C is dominant in camels, human cases are minimal. We reviewed 16 studies (n = 6198) published across seven African countries between 2012 and 2024 to assess human MERS-CoV cases.
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