Due to their evolution in the retroperitoneal space, pheochromocytomas may grow significantly in size and remain asymptomatic for a long period of time. Normal values of urine catecholamine levels must not preclude the diagnosis of these endocrine lesions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028367PMC
http://dx.doi.org/10.1002/ccr3.1566DOI Listing

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