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In-House Virtual Surgery Planning and 3D Printing for Head and Neck Surgery With Free Software: Our Workflow.
Craniomaxillofac Trauma Reconstr
December 2024
Oral and Maxillofacial Surgery, 12 de Octubre University Hospital, Madrid, Spain.
Article Synopsis
- - The study investigates the process of using in-house CAD/CAM technology for head and neck cancer surgeries, particularly focusing on 3D printing biomodels and cutting guides.
- - The goal is to create a validated, cost-effective workflow for a 3D Printing Department in a Spanish university hospital using free software, comparing it with outsourcing options.
- - Results show that an in-house 3D Printing Department is practical, offering benefits like cost savings and faster production times, ultimately improving surgical procedures in the healthcare system.
Post-mortem CT service structures in non-suspicious death investigations.
BJR Open
January 2024
Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3BH, United Kingdom.
Article Synopsis
- Post-mortem CT (PMCT) is becoming a popular, non-invasive option for adult death investigations, addressing pathologist shortages while respecting cultural needs.
- The article discusses various PMCT service structures tailored to different coronial jurisdictions, which face challenges like limited imaging access and logistical issues.
- It further explores operational models for PMCT services, including who leads them, types of CT units used, and reporting structures, offering real-world examples for effective implementation.
Indirect Treatment Comparisons in Healthcare Decision Making: A Targeted Review of Regulatory Approval, Reimbursement, and Pricing Recommendations Globally for Oncology Drugs in 2021-2023.
Adv Ther
November 2024
EVERSANA™, Burlington, ON, Canada.
Introduction: Indirect treatment comparisons (ITCs) evaluate novel treatments compared to appropriate comparators when direct evidence is unavailable or infeasible. The objective of this study was to highlight the prevalence of different ITC methods in oncology drug submissions and to provide insights into how ITCs have been used in recent regulatory approval, reimbursement recommendations, or pricing decisions across various regions and diverse assessment frameworks.
Methods: A targeted literature review was conducted to identify assessment documents for oncology drug submissions that included ITCs.
Real-time Reconstruction of Comminuted Mandibular Fractures Using 3D Printing.
Plast Reconstr Surg Glob Open
March 2024
From the Department of Oral and Maxillofacial Surgery, Rambam Medical Care Center, Haifa, Israel.
Background: Comminuted fractures of the jaws are complex injuries requiring special attention. In the past, treatment included closed reduction using maxillomandibular fixation. With advancements in technology and fixation systems, open reduction became a prevalent option.
View Article and Find Full Text PDFProcess Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis.
J Org Chem
April 2024
EnzyTag B.V, Daelderweg 9, 6361HK, Nuth, Netherlands.
Small molecule therapeutics represent the majority of the FDA-approved drugs. Yet, many attractive targets are poorly tractable by small molecules, generating a need for new therapeutic modalities. Due to their biocompatibility profile and structural versatility, peptide-based therapeutics are a possible solution.
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