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Clinical Manifestations.
Alzheimers Dement
December 2024
Graduate School of Qinghai University, xining, China.
Background: To explore the influence of leisure activities on cognitive function of middle-aged and elderly people living in hypoxia environment.
Method: Using a cross-sectional random sampling survey method, a total of people over 50 years old who have lived for more than 20 years (average altitude 3000m) in Qinghai plateau region were selected. Demography information, chronic medical history, economic and marital status, and 21 leisure activities (including entertainment, mobile phone use, games, sports, travel, social interaction and housework) were investigated.
Clinical Manifestations.
Alzheimers Dement
December 2024
University of California Irvine, Irvine, CA, USA.
Background: Alterations to spatial navigation have been suggested by previous studies to represent an early cognitive marker for those with and at risk of Alzheimer's Disease (AD). However, with most of these studies focusing on spatial memory (usage of formed spatial representations), very little is known about the extent to which spatial exploration (process by which spatial representations are formed) may be altered in AD. The aim of this study is to investigate how spatial exploration behavior may be altered in individuals with and at risk of AD, and the extent to which individuals can be classified into their clinical status based on their exploration behavior.
View Article and Find Full Text PDFToo Soon to Breathe Easy: Trends in Asbestosis Morbidity and Mortality in Wisconsin.
J Occup Environ Med
January 2025
From the Occupational Health Safety and Surveillance Program, Bureau of Environmental and Occupational Health, Wisconsin Department of Health Services, Madison, Wisconsin (P.D.C., K.E.M., K.K.S.M., C.R.M., S.B.); and Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin (P.D.C., K.K.S.M.).
Objectives: This study aimed to describe asbestosis morbidity and mortality in two statewide samples. We considered trends, demographic disparities, and excess mortality.
Methods: We assessed trends and demographic differences in asbestosis morbidity using hospital and emergency department (ED) visits.
Family screening for hypertrophic cardiomyopathy: Initial cardiologic assessment, and long-term follow-up of genotype-positive phenotype-negative individuals.
Int J Cardiol
December 2024
Department of Cardiology, Cardiovascular Institute, Thorax Center, Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands.
Aims: (i) Investigate the prevalence of hypertrophic cardiomyopathy (HCM) in individuals with pathogenic/likely pathogenic (P/LP) gene variants detected through family cascade testing in relatives, and (ii) evaluate phenotypic progression in genotype-positive phenotype-negative (G+/P-) individuals during follow-up.
Results: From 2000 to 2023, 273 individuals underwent cardiologic evaluation following P/LP variant detection through family screening. Upon initial evaluation, HCM was diagnosed in 128 (47 %) individuals.
A sustainable and expedited 'One-Stop' prostate cancer diagnostic pathway to reduce environmental impact and enhance accessibility.
BJUI Compass
December 2024
USC Institute of Urology, Catherine and Joseph Aresty Department of Urology, Keck School of Medicine University of Southern California Los Angeles California USA.
Objective: To assess the carbon footprint, accessibility, and diagnostic performance of an expedited 'One-Stop' prostate cancer (PCa) diagnostic pathway.
Materials And Methods: A total of 1083 consecutive patients undergoing magnetic resonance imaging (MRI) followed by transrectal ultrasound fusion-guided prostate biopsy (PBx) were identified from a prospective database. The patients were divided according to the diagnostic pathway: One-Stop, with MRI and same-day PBx (3 hours apart), or Standard, with MRI followed by a second visit for PBx.
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