AI Article Synopsis
- - Acromegaly is a chronic condition mainly caused by excess growth hormone (GH) from a pituitary tumor, which may impact hearing due to changes in anatomical structures involved in sound perception.
- - A review of existing literature on acromegaly and hearing loss was conducted through a systematic search, identifying only 5 relevant studies in MEDLINE and reference lists.
- - The findings of these studies are inconsistent and yield varied conclusions, highlighting the need for further research with larger patient samples to better understand the relationship between acromegaly and hearing loss.
Article Abstract
Acromegaly is a chronic disease caused by growth hormone (GH) excess due to a GH-secreting pituitary adenoma in most cases. There is reasonable data to presume the possible influence of chronic GH and insulin-like growth factor I (IGF-I) hyperproduction on the anatomical structures involved in normal sound perception, and on its conductive and/or sensorineural part. To review the literature about acromegaly and hearing loss. A systematic literature search was performed using the MEDLINE database, including hand-searching reference lists from original articles. The search was performed using the terms and , and only 5 studies were found. The results are not consistent, but led to different conclusions. Therefore, more studies with greater numbers of patients with acromegaly are needed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033589 | PMC |
| http://dx.doi.org/10.1055/s-0037-1603619 | DOI Listing |
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