Ginseng is a natural product best known for its curative properties in diverse physiological processes such as cancer, neurodegenerative disorders, hypertension, and maintenance of hemostasis in the immune system. In previous decades, there have been some promising studies into the pharmacology and chemistry of ginseng components and the relationship between their structure and function. The emerging use of modified ginseng and development of new compounds from ginseng for clinical studies have been topics of study for many researchers. The present review deals with the anticancer, anti-inflammatory, antioxidant, and chemopreventive effects, and recent advances in microRNA technology related to red ginseng. The review also summarizes the current knowledge on the effect of ginsenosides in the treatment of cancer.
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http://dx.doi.org/10.1016/j.jgr.2017.04.009 | DOI Listing |
Anal Methods
January 2025
International Research Centre for Nano Handling and Manufacturing of China, Changchun University of Science and Technology, Changchun 130022, China.
Atomic force microscopy (AFM) is widely used for the imaging and characterization of biological cells because of its nanoscale spatial resolution and force resolution. However, in the previous studies, the inability to effectively detect the contractile work of cardiomyocytes and the 3D dynamic expressions of their contraction and relaxation behaviors posed significant challenges. Therefore, this work presents a method for the analysis of the contractile work of a single cardiomyocyte by AFM.
View Article and Find Full Text PDFRapid Commun Mass Spectrom
April 2025
Department of Traditional Chinese Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Rationale: Panax quinquefolius L. (PQ), a commonly used traditional Chinese medicine and a food, is usually processed into various products, including white PQ, red PQ (two- or three-time steamed PQ), and black PQ (nine-time steamed PQ). Previous studies demonstrated that volatile components (VOCs) were the important active substances of PQ, which had antibacterial, antiviral, and anti-leukemia activities.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Lanzhou University Second Hospital, Chengguan District, Lanzhou, China.
Background: Colorectal cancer, being 1 of the most significant malignant tumors globally, poses a substantial risk to human health. Unfortunately, its 5-year survival rate stands at a mere 65%. There remains an urgent need for the development of novel treatments to combat this detrimental malignancy effectively.
View Article and Find Full Text PDFPharmacol Res
January 2025
Cancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China; MoE Frontiers Science Center for Precision Oncology, University of Macau, Macau SAR, China; State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macau SAR, China. Electronic address:
J Food Sci
January 2025
College of Pharmacy, Changchun University of Chinese Medicine, Changchun, China.
Ginseng and its processed products are valued as health foods for their nutritional benefits. The traditional forms of processed ginseng include white ginseng, dali ginseng (DLG), red ginseng (RG), and black ginseng (BG). However, the impact of processing on the chemical composition and anti-tumor efficacy of these products is not well understood.
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