AI Article Synopsis
- - Severe combined immunodeficiency (SCID) screening at birth uses T-receptor excision circles to assess newborn immunity and understand maternal health impacts.
- - A study in France showed a small drop in immunity among newborns of HIV-infected mothers.
- - This decrease in immune response is influenced by factors such as prematurity and the infants' African ethnicity.
Article Abstract
Severe combined immunodeficiency screening by measuring T-receptor excision circles at birth allows evaluation of the impact of various maternal conditions on newborn immunity. The slight decrease observed in a French cohort of newborns to HIV-infected mothers can be explained by the confounding factors of prematurity and African descent.
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| http://dx.doi.org/10.1016/j.jpeds.2018.06.008 | DOI Listing |
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