AI Article Synopsis
- The study evaluated oxidative stress in sheep infected with parasites by measuring markers such as malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI).
- It involved 40 sheep split into two groups: healthy (group I) and infected (group II), with blood samples analyzed for MDA, TAC, and TOS using spectrophotometric methods and test kits.
- Results showed that infected sheep had higher levels of MDA, TOS, and OSI, and lower TAC, indicating an imbalance between oxidants and antioxidants due to the infection.
Article Abstract
Introduction: The study aimed at evaluating oxidative stress using malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) markers in sheep naturally infected with (Acari).
Material And Methods: The study was performed on 40 sheep divided into two equal groups: a healthy group (group I) and a group naturally infected with (group II). The sera were obtained by centrifuging blood samples collected from the vena jugularis and serum MDA level changes in the samples were measured spectrophotometrically. Commercially available test kits were used for the measurement of TAC and TOS levels. The percentage ratio of TOS level to TAC level was accepted as OSI.
Results: The serum malondialdehyde, total oxidant status levels, and oxidative stress index increased significantly (P < 0.01) in group II, while the serum total antioxidant capacity levels decreased significantly (P < 0.01) in this group. Negative correlations between total antioxidant capacity and total oxidant status and total antioxidant capacity and malondialdehyde, and a positive correlation between total oxidant status and malondialdehyde were found in infected sheep.
Conclusion: The obtained results indicated the relationship between oxidant/antioxidant imbalance and infection in sheep. Their MDA, TAC, TOS, and OSI markers may be used to determine the oxidative stress in natural infections with .
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894390 | PMC |
| http://dx.doi.org/10.1515/jvetres-2017-0025 | DOI Listing |
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