The multiscale entropy (MSE) measure is now widely used to quantify the complexity of time series. The development of complexity measures for images is also a long-standing goal. Recently, the bi-dimensional version of MSE has been proposed (MSE) to analyze images. The interpretation of MSE curves and the applications to real data are still emergent. Because the coarse-graining step in the MSE computation changes the frequency content of the image, we hypothesized a possible dependence between MSE and the discrete Fourier transform (DFT). To analyze this dependence, synthetic as well as biomedical images are analyzed. Our results reveal that i) the profile of MSE is sensitive to both the amplitude and phase of the DFT; ii) MSE could find applications in the biomedical field. This work brings valuable information for MSE interpretation and opens possibilities to study images from an entropy point of view through spatial scales.
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