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Real-Time Volumetric Free-Hand Ultrasound Imaging for Large-Sized Organs: A Study of Imaging the Whole Spine.
Ultrasound Med Biol
January 2025
Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province, China.
Objectives: Three-dimensional (3D) ultrasound imaging can overcome the limitations of conventional two-dimensional (2D) ultrasound imaging in structural observation and measurement. However, conducting volumetric ultrasound imaging for large-sized organs still faces difficulties including long acquisition time, inevitable patient movement, and 3D feature recognition. In this study, we proposed a real-time volumetric free-hand ultrasound imaging system optimized for the above issues and applied it to the clinical diagnosis of scoliosis.
View Article and Find Full Text PDFChiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications.
Biotechnol Adv
January 2025
Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic. Electronic address:
In nature, various molecules possess spiral geometry. Such helical structures are even prevalent within the human body, represented classically by DNA and three-dimensional (secondary structure) protein folding. In this review, we chose helicenes and helicene-like structures -synthetically accessible carbon-rich molecules- as a compelling example of helically chiral scaffolds.
View Article and Find Full Text PDFDiagnosis of lymph node metastasis in oral squamous cell carcinoma by an MRI-based deep learning model.
Oral Oncol
January 2025
Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, Guangdong, China; Guangdong Province Key Laboratory of Stomatology, Guangzhou, Guangdong, China. Electronic address:
Background: Cervical lymph node metastasis (LNM) is a well-established poor prognosticator of oral squamous cell carcinoma (OSCC), in which occult metastasis is a subtype that makes prediction challenging. Here, we developed and validated a deep learning (DL) model using magnetic resonance imaging (MRI) for the identification of LNM in OSCC patients.
Methods: This retrospective diagnostic study developed a three-stage DL model by 45,664 preoperative MRI images from 723 patients in 10 Chinese hospitals between January 2015 and October 2020.
The feasibility of the adult age estimation 3D-CBCT method on ancient human remains.
J Forensic Odontostomatol
December 2024
Laboratory of Personal Identification and Forensic Morphology, Department of Health Sciences, University of Florence, Florence, Italy.
The age estimation of skeletal remains still represents a central issue not only for the reconstruction of the so-called "biological profile," but mostly for the palaeodemographic investigation. This research aims at verifying the feasibility of the adult age estimation method developed on living people by Pinchi et al. (2015 and 2018), for estimating the age at the death of 37 subjects from ancient populations found in two different Italian necropolis of archaeological interest (Mont'e Prama and Florence, X-IX century B.
View Article and Find Full Text PDFComparative analysis of estimated age by pulp-to-tooth area ratio using CBCT in three different teeth on a subset of Hyderabad population: A preliminary study.
J Forensic Odontostomatol
December 2024
Department of Oral Medicine and Radiology, Army College of Dental Sciences.
Objectives: The study aims to evaluate the pulp-to-tooth area ratio in permanent maxillary central incisors, lateral incisors, and canines for age estimation using three-dimensional cone beam computed tomography images.
Methods: Hundred cone-beam computed tomography (CBCT) images of patients aged between 12-70 years were retrospectively studied using NNT Viewer software version 13. Pulpal and teeth area were evaluated with the "area tool" in the acquired images in all three planes, and the pulp-to-tooth area ratio (PTR) was calculated with the measurements obtained.
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