Objective: To describe the occurrence of immediate transfusion reactions received by the Risk Management Department of Hospital São Paulo.
Method: Cross-sectional and retrospective study which analyzed the notification sheets of transfusion reactions that occurred between May 2002 and December 2016 and were included in the Hemovigilance National System.
Results: One thousand five hundred and forty-eight transfusion reaction notification sheets were analyzed, all of which concerned immediate reactions associated with packed red blood cells (72.5%). The most frequently reported reaction was febrile non-hemolytic transfusion reaction, and among severe and moderate cases, allergic reaction was the most common. The most frequently reported signs and symptoms were hyperthermia, sudoresis, chills, and skin lesions. No differences were observed regarding gender and age, and 90.7% of reactions occurred in patients with Rh+ factor.
Conclusion: This study allowed for a better assessment and understanding of transfusion reactions, which will help to improve the quality of blood circulation and provide greater safety of patients undergoing transfusion therapy.
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http://dx.doi.org/10.1590/S1980-220X2017010603331 | DOI Listing |
Virol J
January 2025
Laboratório de Desenvolvimento Tecnológico em Virologia, Instituto Oswaldo cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.
Background: Nonenveloped viruses, such as hepatitis A virus (HAV) and parvovirus B19 (B19V), are not inactivated by detergents and solvents commonly used to manufacture plasma derivatives. Cases of transfusion-transmitted HAV and B19V have already been described in several countries. This study aimed to determine the incidence of HAV and B19V asymptomatic infections in blood donors from Rio de Janeiro and evaluate the residual risk of transmission to blood derivative recipients.
View Article and Find Full Text PDFTransfus Apher Sci
January 2025
ICMR-National Institute of Immunohaematology (NIIH), 13th Floor, K.E.M Hospital campus, Parel, Mumbai 400012, India. Electronic address:
This case report presents first case of RHD*weak D type 9 in a 38-year-old Indian patient with severe osteoarthritis of the left hip joint scheduled for total hip replacement surgery. During routine blood grouping, an unexpected weak reaction with anti-D was observed. Serological characterization using an extended partial D typing kit characterized the variant as DV.
View Article and Find Full Text PDFHematol Oncol Stem Cell Ther
January 2025
Hematology Laboratory-Blood Bank, Aretaieion Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Transfusion of blood products is a common lifesaving medical procedure in clinical practice. However, it poses the risk of potential adverse reactions for the recipient. Transfusion-associated graft-versus-host-disease (TA-GVHD) is a rare adverse event, fatal in >90% of cases.
View Article and Find Full Text PDFAsian J Transfus Sci
May 2023
Department of Transfusion Medicine and Blood Bank, AIIMS, Raipur, Chhattisgarh, India.
A end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and contains only H antigen. A 25y/M was accepted for blood donation and showed weak/mf reaction with anti-A in forward grouping.
View Article and Find Full Text PDFAsian J Transfus Sci
May 2023
Haemovigilance Programme of India, National Institute of Biologicals, Noida, Uttar Pradesh, India.
Background: Hemovigilance has become one of the important quality check systems of blood transfusion process, but under/non-reporting of transfusion-associated adverse reactions despite the presence of reporting systems emphasize the need to understand the challenges being faced in active reporting of adverse transfusion reactions.
Aim: To identify and document the possible factors leading to under-reporting and impacting the quality of blood transfusion reactions being submitted under Haemovigilance Programme of India (HvPI).
Settings And Design: This was a cross-sectional, observational type study, carried out in six blood banks, two each of government, private, and stand-alone sectors in Delhi National Capital Region enrolled under HvPI.
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