AI Article Synopsis
- Gastric cancer management requires a multidisciplinary approach, incorporating various treatments alongside surgical resection.
- A review of literature from 2000 to 2017 highlights effective therapies like adjuvant chemoradiotherapy, perioperative chemotherapy, and neoadjuvant therapy.
- While combined treatments are generally more effective than surgery alone, the ideal regimen is still uncertain and depends on individual patient factors and tumor specifics.
Article Abstract
Background: The complexity of the management of gastric cancer requires a multidisciplinary evaluation of patients with this tumor. Several treatments have been employed, associated to the surgical resection.
Objective: To review the available therapeutic alternatives for the treatment of gastric adenocarcinoma.
Methods: A review of selected articles on multidisciplinary treatment of gastric adenocarcinoma in the Pubmed and Medline databases between 2000 and 2017 was carried out. The following headings were related: stomach cancer, treatment, chemotherapy and radiotherapy.
Results: There are several valid alternatives, with good results for the treatment of gastric cancer: chemoradiotherapy or chemotherapy in the adjuvant scenario; perioperative chemotherapy; and chemoradiotherapy after neoadjuvance with isolated chemotherapy.
Conclusion: Current evidences suggest that combined multidisciplinary treatment is superior to surgery alone. However, the optimal treatment regimen is not yet established, and depends on a number of factors, especially the type of surgical resection employed. Therefore, the therapeutic decision should be made by a multidisciplinary team, assessing patient's personal characteristics, biology of the tumor, residual disease, risks and side effects.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044205 | PMC |
| http://dx.doi.org/10.1590/0102-672020180001e1373 | DOI Listing |
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