Background: The best site for splenic implant was not defined, mainly evaluating the functionality of the implant.
Aim: To evaluate the effects of autogenous splenic implantation on the subcutaneous tissue in the survival of splenectomized rats.
Method: Twenty-one randomly assigned rats were studied in three groups (n=7): group 1 - manipulation of the abdominal cavity and preservation of the spleen; group 2 - total splenectomy; group 3 - splenectomy and implant of the tissue removed in the subcutaneous. The animals were followed for 90 days postoperatively.
Results: There was a higher mortality in groups 2 (p=0.0072) and 3 (p=0.0172) in relation to group 1. There was no difference between groups 2 and 3 (p=0.9817).
Conclusion: The splenic implant in the subcutaneous is ineffective in the survival of rats submitted to splenectomy.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044191 | PMC |
| http://dx.doi.org/10.1590/0102-672020180001e1364 | DOI Listing |
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