AI Article Synopsis
- A new method for nitrating the aromatic ortho C-H positions on aryl ureas using Fe(NO)·9HO has been developed.
- It employs CuCl·2HO as a catalyst and p-TSA as an additive.
- This reaction shows good compatibility with different functional groups and provides the desired products in moderate to excellent yields.
Article Abstract
A novel protocol for the aromatic ortho C-H nitration of aryl ureas with Fe(NO)·9HO is developed. The reaction utilizes CuCl·2HO as catalyst and p-TSA as additive, showing good functional group tolerance and furnishing the desired products in moderate to excellent yields.
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| http://dx.doi.org/10.1021/acs.joc.8b01016 | DOI Listing |
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