Intra-parenchymal sialolithiasis and subsequent fibrosis of the submandibular salivary glands is a rare disorder. The resulting swelling, pain, and infection derives affected patients to seek treatment. We present the case of an 85-years-old Saudi male patient who suffered from repeated swelling and infection in the left submandibular region which was misdiagnosed and treated for over 60 years as dental infection, infected skin sebaceous gland or lipoma. The presented case represents the largest intra-glandular submandibular stone with the longest duration ever reported in the medical literature.
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http://dx.doi.org/10.15537/smj.2018.7.22265 | DOI Listing |
Cureus
November 2024
Internal Medicine, Johnston Memorial Hospital, Abingdon, USA.
Ludwig's angina (LA) is a rapidly progressive cellulitis-causing airway obstruction that can spread through fascial planes to the floor of the mouth and into the mediastinum. Early recognition and treatment are essential for preventing potentially fatal complications. Diagnosis is based on clinical suspicion and confirmed through CT and ultrasound (US).
View Article and Find Full Text PDFAm J Otolaryngol
December 2024
Department of Surgery, Division of Otolaryngology, Dayton, OH, USA. Electronic address:
Introduction: Pleomorphic adenoma is the most common neoplasm of the major salivary glands, and can undergo malignant transformation to carcinoma ex-pleomorphic adenoma (CXPA) in untreated patients.
Case Presentation: Our case describes a 56-year-old male with a 15-year history of slowly growing expansive right-sided neck. He underwent excision of the neck mass, neck dissection, and pectoralis flap reconstruction.
Bull Tokyo Dent Coll
December 2024
Department of Oral Pathobiological Science and Surgery, Tokyo Dental College.
Sialolithiasis is a common disease of the salivary glands. This report describes a rare case of a submandibular gland sialolithiasis that grew over an extended period. The patient was a 72-year-old woman who presented with a mass in the right submandibular gland that had remained untreated for approximately 34 years.
View Article and Find Full Text PDFInt Immunopharmacol
December 2024
Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China; Shanxi Key Laboratory of Rheumatism Immune Microecology, Taiyuan, Shanxi, China; Shanxi Precision Medical Engineering Research Center for Rheumatology, Shanxi, China. Electronic address:
Background: Paclitaxel is a highly effective chemotherapeutic agent used to treat breast, ovarian, and other cancers. At the same time, paclitaxel causes peripheral neuropathy as a side effect in 45%-70% of patients.
Aim: The aim of the study was to investigate the effect of paclitaxel-induced peripheral neuropathy on the development of pathological changes in the salivary glands of animals and to explore the possibility of correction of the identified changes with vitamin B/ATP complex.
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