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Mobile Colistin Resistance and Plasmid-Mediated Quinolone Resistance Genes in from China, 1993-2019.
Foodborne Pathog Dis
July 2024
Jiangsu Key Laboratory of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Plasmid-mediated quinolone resistance (PMQR) genes and mobile colistin resistance (MCR) genes in () have been widely identified, which is considered a global threat to public health. In the present study, we conducted an analysis of MCR genes (, , , , and ) and PMQR genes [, , , , , , , , , and ] in from China, 1993-2019. From the 3,663 isolates examined, 1,613 (44.
View Article and Find Full Text PDFPolymyxin Resistance in : Exploring Mutations and Genetic Determinants of Non-Human Isolates.
Antibiotics (Basel)
January 2024
Adolfo Lutz Institute, São Paulo 01246-000, SP, Brazil.
Until 2015, polymyxin resistance was primarily attributed to chromosomal mutations. However, with the first report of mobile colistin resistance () in commensal from food animals in China, the landscape has changed. To evaluate the presence of polymyxin resistance in spp.
View Article and Find Full Text PDFCharacterization of quinolone resistance in Salmonella enterica serovar Typhimurium and its monophasic variants from food and patients in China.
J Glob Antimicrob Resist
December 2023
Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Key Laboratory of Agricultural Microbiomics and Precision Application, Ministry of Agriculture and Rural Affairs, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, China. Electronic address:
Article Synopsis
- - The study investigated quinolone resistance in *Salmonella enterica serovar Typhimurium* and its variation *Salmonella enterica serovar 1,4,[5],12:i:-* from food and patients in China, assessing their susceptibility and genetic mutations.
- - Results showed high resistance rates to nalidixic acid, reduced susceptibility to ciprofloxacin and levofloxacin, and frequent mutations in the *gyrA* gene, along with several other resistance genes identified in the isolates.
- - The findings indicate a significant public health threat due to the clonal spread and horizontal gene transfer of quinolone resistance among these Salmonella strains in China.
First Emergence of NDM-5 and OqxAB Efflux Pumps Among Multidrug-Resistant Isolated from Pediatric Patients in Assiut, Egypt.
Infect Drug Resist
September 2023
Microbiology and Immunology Department, Faculty of Pharmacy, Port Said University, Port Said City, 42526, Egypt.
Introduction: New Delhi metallo-β-lactamase (NDM)-producing poses a high risk, especially among Egyptian pediatric patients who consume carbapenems antibiotics very widely and without adequate diagnostic sources. In addition, presence of efflux pump genes such as increases resistance against many groups of antimicrobials which exacerbates the problem faced for human health. This study aimed to determine NDM variants among strains isolated from pediatric patients in Egypt, analyze the presence of genes, and molecular characterization of -positive .
View Article and Find Full Text PDFSerotyping and Antimicrobial Resistance Profiling of Multidrug-Resistant Non-Typhoidal from Farm Animals in Hunan, China.
Antibiotics (Basel)
July 2023
College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Non-typhoidal (NTS) is a foodborne pathogen and a prevalent causative agent for disease outbreaks globally. The enterica serovar 4,[5],12:i:- (S.4,[5],12:i:-) belongs to the monophasic variant of , which is of current global concern.
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