AI Article Synopsis
- - Two new compounds, 2-pyranones and isocoumarin derivatives named maculanslines A-D, were discovered in a plant pathogenic fungus, alongside seven previously known compounds.
- - The structures and configurations of these compounds were determined using advanced techniques like high-resolution mass spectrometry and nuclear magnetic resonance.
- - All 11 compounds were tested for their ability to inhibit -glucosidase, revealing that one compound demonstrated moderate activity with an IC value of 74.35 μM.
Article Abstract
Two new 2-pyranones and two new isocoumarin derivatives, maculanslines A-D (), together with seven known compounds (), were isolated from the plant pathogenic fungus . Their planar structures and absolute configuration were elucidated by comprehensive spectroscopic techniques including high-resolution electrospray ionization mass spectrum, 1D and 2D nuclear magnetic resonance, as well as electronic circular dichroism. All 11 compounds were tested for their inhibitory activity against -glucosidase. Compound showed moderate inhibitory activity against -glucosidase with IC of 74.35 μM.
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| http://dx.doi.org/10.1080/10286020.2018.1485661 | DOI Listing |
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