Antilithiatic Potential of , , , and .

J Pharm Bioallied Sci

School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India.

Published: January 2018

Objective: The study aims at the exploration of calcium oxalate (CaO) crystal growth inhibition potential of , , , and ethyl acetate fraction rich in polyphenol and flavonoid.

Materials And Methods: Ethyl acetate fraction was separated from the hydromethanolic extract of , , , and followed by quantitative analysis for total polyphenol and flavonoid content. Ethyl acetate fraction of all the plants were subjected to screening for the inhibition of CaO crystals growth induced by sodium oxalate.

Results: The results signify rich presence of polyphenols and flavonoids in and ethyl acetate fractions followed by and . Ethyl acetate fractions of shoot, fruit, and leaf have excellent CaO crystal growth inhibition potential based on both the comparative concentration and the time level to achieve IC.

Conclusion: The study outcome substantiates potential CaO crystal dissolution and crystal growth inhibition properties of , and . Rich presence of caffeic acid, ferulic acid, and luteolin in ethyl acetate fraction of leaf, and chebulinic acid, chebulagic acid, gallic acid, ellagic acid, and quercetin of may have produced prominent crystal aggregation inhibition response.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998695PMC
http://dx.doi.org/10.4103/JPBS.JPBS_18_18DOI Listing

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