Purpose: Antibacterials are commonly prescribed to Pediatric Intensive Care Unit (PICU) patients. However, inappropriate antibacterial prescriptions lead to increases in antibacterial resistance, treatment cost, duration of treatment, and poor clinical outcome. The antibacterial utilization study assesses the prescription patterns and if necessary recommends the interventions to improve antibacterial prescriptions. Hence, the present prospective groundwork was conducted.

Materials And Methods: The study was conducted over the period of 6 months (April 18 to October 20, 2014). The demographics and drug use details were captured daily from patients admitted to PICU to assess World Health Organization indicators.

Results: A total of 200 patients enrolled, among them 119 males and 81 females. There were 12.46 (±6.16) drugs prescribed per patient, of which 2.38 (±1.48) were antibacterials. Among the total drug prescribed, 18.49% were antibacterials and 97% patients received at least one antibacterial. Ceftriaxone (49.48%) was the most commonly prescribed antibacterial, while imipenem (2.58%) and colistin (2.06%) use was very low. A total of 80.95% antibacterials were prescribed by generic name, 94.88% were administered intravenously, and 80.76% were prescribed from hospital pharmacy. The average length of PICU stay was 6.15 days (±6.20), the average length of antibacterial treatment was 6.08 days (±6.27), and the average length of empirical antibacterial treatment was 5.50 days (±5.40). The cost of antibacterial therapy per patient was Indian rupees 824.64 (±235.35). In 27 patients, bacterial culture test was positive and of whom 21 received antibacterials as per sensitivity pattern.

Conclusions: The use of antibacterials was not indiscriminately high but more prescriptions per sensitivity pattern are required.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020630PMC
http://dx.doi.org/10.4103/ijccm.IJCCM_365_17DOI Listing

Publication Analysis

Top Keywords

average length
12
antibacterial
9
antibacterial utilization
8
utilization study
8
pediatric intensive
8
intensive care
8
care unit
8
commonly prescribed
8
antibacterial prescriptions
8
antibacterial treatment
8

Similar Publications

Background: Amalgamation of metal-tolerant plant growth promoting rhizobacteria (PGPR) with biochar is a promising direction for the development of chemical-free biofertilizers that can mitigate environmental risks, enhance crop productivity and their biological value. The main objective of the work includes the evaluation of the influence of prepared bacterial biofertilizer (BF) on biometric growth parameters as well as physiological and biochemical characteristics of rapeseed ( L.) at copper action.

View Article and Find Full Text PDF

SeqLengthPlot v2.0: an all-in-one, easy-to-use tool for visualizing and retrieving sequence lengths from FASTA files.

Bioinform Adv

November 2024

Department of Biology and Evolution of Marine Organisms (BEOM), Stazione Zoologica Anton Dohrn, Roma I-00198, Italy.

Motivation: Accurate sequence length profiling is essential in bioinformatics, particularly in genomics and proteomics. Existing tools like SeqKit and the Trinity toolkit provide basic sequence statistics but often fall short in offering comprehensive analytics and plotting options. For instance, SeqKit is a very complete and fast tool for sequence analysis, delivering useful metrics (e.

View Article and Find Full Text PDF

Background/aim: Despite Türkiye's relatively young population, there is an emerging trend of earlier diagnoses of chronic diseases, including heart failure (HF). This study aims to shed light on survival rates, potential influences of guideline-directed therapies, and sex-based differences necessitating personalized management in HF.

Materials And Methods: We conducted a nationwide retrospective cohort analysis of 2,722,151 patients with HF using deidentified data from the Turkish Ministry of Health's national electronic database.

View Article and Find Full Text PDF

Objective: The COVID-19 pandemic has placed unprecedented strain on healthcare systems, mainly due to the highly variable and challenging to predict patient length of stay (LOS). This study aims to identify the primary factors impacting LOS for patients before and during the COVID-19 pandemic.

Methods: This study collected electronic medical record data from Zhongnan Hospital of Wuhan University.

View Article and Find Full Text PDF

Characterization and functionality of 1003 isolated from chicken cecum against .

Front Cell Infect Microbiol

December 2024

Postdoctoral Research Workstation, Heilongjiang Academy of Agricultural Sciences, Harbin, China.

Lactic acid bacteria are widely regarded as safe alternatives to antibiotics in livestock and poultry farming and have probiotic potential. () is a prominent component of pigeon crop microbiota; however, its function is unknown. In this study, a strain of 1003 from pigeon cecum was identified by combining whole genome sequencing and phenotypic analysis, and its safety and probiotic properties were studied.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!