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Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manufacturing Practice Conditions in Hospital Pharmacy Compounding Facilities.
Pharmaceutics
January 2025
Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen (UMCG), 9713 GZ Groningen, The Netherlands.
Parenteral drug products manufactured under GMP conditions should be visually inspected for defects and particulate contamination by trained and qualified personnel. Although personnel qualification is required, no practical protocols or formal guidelines are available for the development of qualification test sets (QTSs) used for qualification procedures. The current practice is to either procure a standardized QTS from a commercial supplier or amass sufficient manufacturing rejects during visual inspection procedures to compile in-house QTSs.
View Article and Find Full Text PDFOriginal Personalized Reconstruction Method for Certain Large Tumors of the Lower Lip (Not Including Oral Commissures).
Medicina (Kaunas)
December 2024
Faculty of Dental Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 8, Victor Babes Str., 400347 Cluj-Napoca, Romania.
: Surgical treatment of extensive tumors of the lower lip generates important defects in its structure and functions. Over time, a multitude of reconstruction options for these defects have been imagined. Unfortunately, the majority involve the use of both local and regional flaps, which either lack labial structure or disorganize the oral commissures as nodal oral function points.
View Article and Find Full Text PDF[Clinical dilemma and indication selection of restoration for permanent tooth defects in adolescents].
Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
Adolescence is defined as a population ranging from ten to nineteen years old. Permanent teeth in adolescents are of critical significance as they are actively involved in mastication, contribute to aesthetic appearance, play a role in pronunciation, and are integral to the growth and development of the stomatognathic system. Specifically, permanent teeth in adolescents comprise those with incomplete root development and those with complete root development but unstable gingival margin positions.
View Article and Find Full Text PDFLessons Learned in Virtual Launch of an Antenatal Opioid Exposure Study During the COVID-19 Pandemic.
Nurs Res
January 2025
RTI International, Research Triangle Park, NC.
Background: The COVID-19 pandemic prompted researchers to develop new ways to design and launch studies and recruit and retain participants. Pregnant women and infants are considered vulnerable populations in research, and families affected by substance use are particularly difficult to recruit and retain. Recruitment for studies involving medical technologies such as MRI can also be difficult due to misconceptions and fear of the technologies.
View Article and Find Full Text PDFInequity in treatment access for child mental health services in England: analysis of administrative national data for 2021-2022.
BJPsych Bull
January 2025
Public Health Directorate (East of England), NHS England, Fulbourn, UK.
Aims And Method: An equitable child mental health service provides access to treatment proportionally to the need of individual demographic groups. Despite qualitative and survey-based evidence of barriers disadvantaging some demographic groups, it is not well understood how these barriers translate into quantifiable inequities. We calculated the treatment access rate for English children aged 6-16 years in 2021-2022, using the patient-level Mental Health Services Data Set and Mental Health of Children and Young People Survey.
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