From Dental to Mental Institutions: An American Dentist and a British Psychiatrist Highlight Insanity Following Nitrous-Oxide Administration.

J Anesth Hist

Anesthesiology and Perioperative Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, OH 44106-6031, USA; Oral and Maxillofacial Surgery, Case Western Reserve University School of Dental Medicine, 2124 Cornell Rd, Cleveland, OH 44106-3804, USA; Honorary Curator and Laureate of the History of Anesthesia, Wood Library-Museum of Anesthesiology, American Society of Anesthesiologists, 1061 American Ln, Schaumburg, IL 60173-4973, USA. Electronic address:

Published: April 2018

In 1887, American dentist Samuel J. Hayes published reports associating unoxygenated anesthetics with asphyxia and insanity, and then British psychiatrist George H. Savage published a report of cases of insanity following nitrous-oxide anesthesia in British journals.

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http://dx.doi.org/10.1016/j.janh.2018.02.002DOI Listing

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