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Expression of claudin-18.2 in cholangiocarcinoma: a comprehensive immunohistochemical analysis from a German tertiary centre.
Histopathology
December 2024
Goethe University Frankfurt, Medical Clinic 1, University Hospital, Frankfurt am Main, Germany.
Aims: Anti-claudin-18.2 (CLDN18.2) therapy was recently approved for the treatment of gastric or gastro-oesophageal junction adenocarcinoma.
View Article and Find Full Text PDFTherapies in Exotic Animal Gastroenterology.
Vet Clin North Am Exot Anim Pract
December 2024
Zoological Medicine Service, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, 2065 W. Farm Road, Stillwater, OK 74078, USA. Electronic address:
This article reviews treatment of gastrointestinal (GI) disorders in exotic companion mammal species, birds, reptiles, amphibians, and fish. Treatment of GI stasis involves fluids, nutrition, and analgesia; there is minimal evidence suggesting prokinetics are useful. Research has evaluated the efficacy of various appetite stimulants in several exotic animal species.
View Article and Find Full Text PDFDevelopment of a New Score Based on Image Defined Risk Factors to Standardize Surgical Risk in Neuroblastoma Resection - A SIOPEN Collaborative Study.
J Pediatr Surg
December 2024
Pediatric Surgery, Dipartimento di Medicina di Precisione e Rigenerativa a Area Jonica, Azienda Ospedaliera-Universitaria Consorziale Ospedale Pediatrico Giovanni XXIII, Bari, Italy.
Background And Aims: Image Defined Risk Factors (IDRFs) assess surgical risk in neuroblastoma (NB) and guide neoadjuvant therapy. Despite chemotherapy IDRFs may persist in 70 % of cases. Several studies have suggested that not all IDRFs hold equal significance and that the presence of an IDRF does not inherently signify unresectability.
View Article and Find Full Text PDFHealthy lifestyle and metabolic associated steatotic liver disease: a study of the efficacy of fatty liver regression.
Clin Transl Gastroenterol
December 2024
Health Management Center, Affiliated Nanhua Hospital, University of South China, Hengyang 421002, China.
Background: Obesity is the primary cause of metabolic associated steatotic liver disease (MASLD). Healthy lifestyle management has potential value in the treatment of MASLD.
Methods: A total of 150 patients with MASLD diagnosed at the Health Management Center of our hospital were enrolled and randomly divided into a traditional treatment (control group, n=75) and healthy lifestyle group (observation group, n=75).
Dorsal Root Ganglion Stimulation for Chronic Pelvic Pain Secondary to Endometriosis.
Neuromodulation
December 2024
Functional and Pain Clinic, Sao Paulo, SP, Brazil; Pediatric Neurosurgery, Washington University in St. Louis, St Louis, MO, USA. Electronic address:
Introduction: Chronic pelvic pain (CPP) is a multifaceted condition that poses significant challenges in clinical management owing to its complex and varied pathophysiology, including neuropathic, somatic, visceral, and musculoskeletal components. Endometriosis is frequently associated with CPP, necessitating a comprehensive, multimodal treatment strategy. This approach typically includes physical and behavioral therapy, pharmacologic interventions, surgical management of endometriosis, and various pain-modulating procedures.
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