Background: The clinical impact of a decrease in impedance during radiofrequency catheter ablation (RFCA) has not been fully clarified. The aim of the study was to analyze the impact of impedance decrease and to determine its optimal cutoff value during RFCA.

Methods: We evaluated 34 consecutive patients (total 3264 lesions, mean age 66 ± 8.7 years, 10 females) who underwent their first ablation for atrial fibrillation (AF). The impedance decrease, average contact force (CF), application time, force-time integral (FTI), product of impedance decrease and application time (PIT), and the product of impedance decrease and FTI (PIFT) were measured for all lesions. Levels of cardiac troponin I (TrpI) were measured for assessment of myocardial injury. The incidence of intraprocedural pulmonary vein-left atrium reconnection or dormant conduction (reconnection) was determined. The relationships between the ablation parameters and the increase in TrpI (ΔTrpI) were evaluated. The predictive value of the parameters for reconnection was assessed using receiver operating characteristic (ROC) curve analysis.

Results: Reconnection was detected in 18 patients. Average FTI and PIT were significantly correlated with ΔTrpI (FTI: = .19, = .0090, PIT: = .21, = .0058). PIFT was correlated with ΔTrpI and was the best of the three indexes (PIFT: = .29, = .0010). In ROC curve analysis, the area under the curve for predicting reconnection was 0.71 and the optimal cutoff value was 5200 for PIFT (sensitivity 78%, specificity 63%).

Conclusion: The combination of CF and a decrease in impedance could be important in the evaluation of myocardial lesions and reconnection during RFCA.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009992PMC
http://dx.doi.org/10.1002/joa3.12056DOI Listing

Publication Analysis

Top Keywords

impedance decrease
20
impact impedance
8
atrial fibrillation
8
decrease impedance
8
optimal cutoff
8
application time
8
product impedance
8
roc curve
8
correlated Δtrpi
8
decrease
7

Similar Publications

Introduction: Obesity is a growing public health issue, especially among young adults, with long-term management strategies still under debate. This prospective study compares the effects of caloric restriction and isocaloric diets with different macronutrient distributions on body composition and anthropometric parameters in obese women during a 12-week weight loss program, aiming to identify the most effective dietary strategies for managing obesity-related health outcomes.

Methods: A certified clinical nutritionist assigned specific diets over a 12-week period to 150 participants, distributed as follows: hypocaloric diets-low-energy diet (LED, 31 subjects) and very low-energy diet (VLED, 13 subjects); isocaloric diets with macronutrient distribution-low-carbohydrate diet (LCD, 48 subjects), ketogenic diet (KD, 23 subjects), and high-protein diet (HPD, 24 subjects); and isocaloric diet without macronutrient distribution-time-restricted eating (TRE, 11 subjects).

View Article and Find Full Text PDF

Changes in muscle-to-fat ratio are associated with lung function decline and airflow obstruction in the general population.

Respir Res

December 2024

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: The long-term relationship between body composition and lung function has not yet been fully demonstrated. We investigated the longitudinal association between muscle-to-fat (MF) ratio and lung function among middle-aged general population.

Methods: Participants were enrolled from a community-based prospective cohort between 2005 and 2014.

View Article and Find Full Text PDF

Objective: to assess the impact of stressful life events occuring with the period of restrictive measures introductionconnected to the COVID-19 pandemic and during the full-scale Russian aggression, on the anthropometric indicators and body composition of children aged 10-17 years.

Materials And Methods: The research group consisted of 56 boys and 70 girls aged 10-17 years who lived in radioactively contaminated areas of Zhytomyr, Rivne, and Kyiv regions with a soil contamination density of 137Cs from 18 kBq/m2 to 235 kBq/m2. The impact of stressful factors was assessed using the stress perception scale (PSS-10).

View Article and Find Full Text PDF

In-situ synthesis of FeS nanoparticles enhances Sulfamethoxazole degradation via accelerated electron transfer in anaerobic bacterial communities.

Water Res

December 2024

College of Water Sciences, Beijing Normal University, Beijing 100875, China; Beijing ENFI Environmental Protection Co., Ltd., Beijing, 100038, China.

The impact of nanominerals on microbial electron transfer and energy metabolism strategies during pollutant degradation remains uncertain. This study used in situ synthesized FeS nanoparticles (FeS NPs) to increase the degradation efficiency of SMX by anaerobic bacterial communities from 25.80 % to 47.

View Article and Find Full Text PDF

Research on hydroxyapatite (HAP) coatings for bone tissue applications has been investigated for decades due to their significant osteoconductive and bioactivity properties. HAP closely resembles the mineral component of human bone, making it ideal for biomedical applications such as implants. This study investigates the synthesis of hydroxyapatite nanoparticles (HAP-NPs) via the microemulsion method, which is essential for creating HAP coatings on the Ti-6Al-4V substrate.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!