The ability to manipulate small objects with focused laser beams opens a broad spectrum of opportunities in fundamental and applied studies, for which precise control over mechanical path and stability is required. Although conventional optical tweezers are based on refractive optics, the development of compact trapping devices that could be integrated within fluid cells is in high demand. Here, a plasmonic polarization-sensitive metasurface-based lens, embedded within a fluid, is demonstrated to provide several stable trapping centers along the optical axis. The position of a particle is controlled with the polarization of the incident light, interacting with plasmonic nanoscale patch antennas, organized within overlapping Fresnel zones of the lens. While standard diffractive optical elements face challenges in trapping objects in the axial direction outside the depth of focus, bifocal Fresnel meta-lens demonstrates the capability to manipulate a bead along a 4 μm line. An additional fluorescent module, incorporated within the optical trapping setup, was implemented and enabled the accurate mapping of optical potentials via a particle-tracking algorithm. Auxiliary micro- and nanostructures, integrated within fluidic devices, provide numerous opportunities to achieve flexible optomechanical manipulation, including transport, trapping, and sorting, which are in high demand for lab-on-a-chip applications and many others.
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http://dx.doi.org/10.1021/acs.nanolett.8b01844 | DOI Listing |
J Contemp Brachytherapy
October 2024
Department of Radiation Oncology, East Carolina University, Greenville, North Carolina, USA.
Purpose: To investigate sensitivity of contributing factors to heterogeneity corrections in ocular brachytherapy using iodine-125 (I) Collaborative Ocular Melanoma Study (COMS) plaques.
Material And Methods: Using egs_brachy, Monte Carlo (MC) simulations were performed for I COMS plaques (model: IsoAid IAI-125A). Homogeneous dose (D) was estimated under the American Association of Physicists in Medicine Task Group-43 assumptions, with 85 Gy prescribed to a 5 mm depth.
Biochem Genet
December 2024
Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated People's Hospital of Northwest University, No. 21 Jiefang Rd, Xi'an, 710004, Shaanxi, China.
Retinoblastoma (RB) is an aggressive form of eye cancer. β-Asarone is a bioactive component isolated from the medicinal plant Acorus tatarinowii Schott and has anticancer effects on various human cancers. However, reports regarding the role of β-Asarone in RB remain limited.
View Article and Find Full Text PDFCell Mol Neurobiol
December 2024
Laboratory of Veterinary Biochemistry, College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju, 63243, South Korea.
Chronic exposure to prenatal stress can impair neurogenesis and lead to irreversible cognitive and neuropsychiatric abnormalities in offspring. The retina is part of the nervous system; however, the impacts of prenatal stress on retinal neurogenesis and visual function remain unclear. This study examined how elevated prenatal glucocorticoid levels differentially affect retinal development in the offspring of pregnant mice exposed to chronic unpredictable mild stress (CUMS).
View Article and Find Full Text PDFExp Eye Res
December 2024
Department of Ophthalmology, Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated People's Hospital of Northwest University, Xi'an 710004, China. Electronic address:
Posterior capsule opacification (PCO) is the most common complication after cataract surgery. In this study, we used transforming growth factor beta-2 (TGF-β2)-induced SRA01/04 cells to mimic PCO cell model and explored the functions and underlying mechanisms of specific protein 1 (SP1) in TGF-β2-induced SRA01/04 cell development. MTT assay and EdU assay were carried out to explore the proliferation of SRA01/04 cells.
View Article and Find Full Text PDFSci Data
December 2024
Key Laboratory of Photoelectronic Imaging Technology and System of Ministry of Education of China, School of Optics and Photonics, Beijing Institute of Technology, Beijing, 100081, China.
Polarization multispectral imaging has advanced significantly due to its robust information representation capability. Imaging application requires rigorous simulation evaluation and experimental validation using standardized datasets. However, the current full-Stokes polarization multispectral images (FSPMI) dataset, while providing simulation data, is limited by image drift and spectral bands.
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